Physicians in the Division undertake clinical trials in patients with chronic kidney disease to yield new information to answer difficult clinical questions. Many of these trials are large, multicenter undertakings with funding from either NIH or the pharmaceutical industry.
Recent clinical trials include the HALT Progression in PKD, part of the Polycystic Kidney Disease Clinical Trials Network); the TEMPO 3/4 study, addressing the efficacy of the vasopressin-receptor antagonist tolvaptan to slow progression of polycystic kidney disease; and the Blood Pressure in Dialysis (BID) Study
Historically, physician-scientists in the Division have participated in landmark clinical trials such as the NIDDK-sponsored MDRD (Modification of Diet in Renal Disease) Study, a randomized trial of diet and blood pressure control in CKD and the Hemodialysis (HEMO) Study, comparing the standard dose of dialysis with high dose of dialysis.
View open clinical trials at Tufts Medical Center >