Center for Complementary and Integrative Medicine


The Tufts Center for Complementary and Integrative Medicine (TCIM) is a research and education-based center within the Division of Rheumatology in the Department of Medicine at Tufts Medical Center.

The primary mission of the TCIM is to improve health outcomes for patients with chronic medical conditions. The TCIM focuses on the rigorous evaluation and investigation of cost-effective methods of Complementary and Alternative Medicine (CAM) therapies. The TCIM strives to integrate evidence-based, multi-disciplinary therapies into conventional care plans for chronic disease prevention and treatment in order to provide the highest quality of clinical care to patients. The TCIM fosters informed and knowledgeable patients, doctors, and researchers through education fueled by national and international collaboration.


The TCIM has three major areas of focus:

  • To conduct clinical research projects in therapies, specifically mind-body medicines.
  • To provide ongoing professional development training for predoctoral and postdoctoral candidates and related healthcare professionals.
  • To implement and integrate scientific, evidence-based therapies into conventional medical practice, including Tai Chi mind-body therapy, acupuncture, and massage therapy.

Ongoing Projects

The TCIM is currently recruiting for three large NIH-funded clinical trials, please click on each title to learn more our goals and how to enroll:

Tai Chi and Physical Therapy for Knee Osteoarthritis

For more information on this study, please view the NIH clinical trials database

Tai Chi and Aerobic Exercise for Fibromyalgia

For more information on this study, please view the NIH clinical trials database.

Tai Chi Mind-Body Exercise for Post-traumatic Stress Disorder in Military Populations

Principal Investigator + Research Team

Chenchen Wang, MD, MSc
Director, Center for Complementary and Integrative Medicine

Employment Opportunities

We are currently seeking candidates for a post-doctoral research fellow and a research assistant/coordinator. These positions will conduct supervised research in the fields of rheumatology and CAM. To learn more about these positions, please visit the Tufts Medical Center Careers website.

Selected Publications

1.  Wang, C. Challenges for the Future of Complementary and Integrative Care. 2014: Health Care Current Reviews 2: e102. doi: 10.4172/hccr.1000e102      

2.  Morgan N, Irwin M, Chung M, Wang C. The Effects of Mind-Body Therapies on the Immune System: Meta-Analysis. PLoS ONE 2014; 9(7): e100903. doi:10.1371/journal.pone.0100903

3.  Gowri Raman G, Zhang, Y, Minichiello VJ, D'Ambrosio, CM, Wang C. Tai Chi Improves Sleep Quality in Healthy Adults and Patients with Chronic Conditions: A Systematic Review and Meta-analysis. Journal of Sleep Disorders & Therapy. 2013; 141.2-6. Doi:10.4172/2167-0277.1000141.

4.  Wang C.  Complementary and Alternative Medicine and Osteoarthritis. Int J Integr Med, 2013, 1, 69-73

5. Wang C. Role of Tai Chi in the Treatment of Rheumatologic Diseases. Current  Rheumatology Reports. 2012;14: 598-603.

6.  Bannuru, RR, Samuel A, Wang C. How Effective is Tai Chi Mind-body Therapy for Knee Osteoarthritis?  A Systematic Review and Meta-Analysis. Osteoarthritis and Cartilage. 2012; 20 S281.

7.  Wang C. Complementary and Alternative Medicine in the Treatment of Rheumatoid Arthritis. Open Access Publisher. Arthritis - Treatment, ISBN 978-953-307-850-2. January 2012.

8. Yuan W, Bannuru RR, Kong L, Cheng Y, McAlindon T, Fang M, Wang C.  Massage Therapy on Pain Relief for Knee Osteoarthritis. Osteoarthritis and Cartilage. 2012; 20 S282.

9. Wong J, Wang C. Cost-effectiveness of Tai Chi Mind-body Exercise for the Treatment of Fibromyalgia. Arthritis and Rheumatism. 2012; 64 suppl.10: S1121.

10Wang C.  Beyond Drugs, Can Tai Chi Mind-body Exercise be an Alternative Treatment Rheumatoid Arthritis? International Journal of Clinical Rheumatology.  2011; 6: 477-479.

11.  Wang C. Tai Chi and Rheumatic Diseases. Rheumatic Disease Clinics of North America. 2011; 37: 19-32.

12. Wang C, Schmid C, Kalish R, Yinh J, Rones R, Goldenberg D, McAlindon T. Tai Chi is Effective in Treating Fibromyalgia: A Randomized Controlled Trial. The New England Journal of Medicine. 2010; 363: 743-54.

13. Wang C, Bannuru R, Ramel J, Kupelnick B, Scott, T, Schmid C. Tai Chi on Psychological Well-being: Systematic Review and Meta-analysis. BMC, Complementary and Alternative Medicine.  2010; 23: 1186-1472.

14. Wang C, Schmid C, Hibberd P, Roubenoff R, Kalish R, Rones R, McAlindon T. Tai Chi is Effective in Treating Knee Osteoarthritis: A Randomized Controlled Trial. Arthritis & Rheum. 2009; 61: 1545-1553.

15. Gloria Y, Wang, C, Wayne P, Phillips R Tai Chi Exercise for Patients with Cardiovascular Conditions and Risk Factors,ASystematic Review.J Cardiopulm Rehab Prev. 2009, 29 (3):152-60.711.   

16. Wang, C, DePablo, P, Chen XY, Schmid C, McAlindon T.  Acupuncture for Pain Relief in Patients with Rheumatoid Arthritis: A Systematic Review. Arthritis & Rheum. 2008; 59: 1249-1256.

17. Wang C.  Tai Chi Improves Pain and Functional Status in Adults with Rheumatoid Arthritis: Results of a Pilot Single-Blinded Randomized Controlled Trial.  Medicine and Sport Science. 2008; 52; 218-229.

18. Wang C. Schmid C, Hibberd P, Roubenoff R, Kalish R, McAlindon T. Tai Chi for Treating Knee Osteoarthritis: Designing a Long-term Follow up Randomized Controlled Trial. BMC, Musculoskeletal Disorder. 2008; 9: 1471-2472.

19. Yeh GY, Wang C, Wayne PM, Phillips RS.  The Effect of Tai Chi Exercise on Blood Pressure: A Systematic Review.  Prev Cardiology. 2008; 11: 82-89.

20.  Wang C, Harris WS, Chung M, Lichtenstein AH, Balk EM, Kupelnick B, Jordan HS, and Lau J. N-3 Fatty acids from Fish or Fish-oil Supplements, but not Alpha-Linolenic Acid, Benefit Cardiovascular Outcomes in Primary and Secondary Prevention Studies: A Systematic Review. American Journal of Clinical Nutrition. 2006; 84: 5-17.

21. Wang C, Collet J,  Lau J. The Effect of Tai Chi on Health Outcomes in Patients with Chronic Conditions: A Systematic Review. Archives of Internal Medicine. 2004; 164: 493-501.

Contact Us

Tel:  617-636-3251
Fax:  617-636-1542