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Arthur S. Tischler, MD
Surgical Pathologist; Professor, Tufts University School of Medicine
Department + Services
Pathology and Laboratory Medicine
Clinical Focus Areas
General surgical pathology, endocrine pathology
Research Focus Areas
Endocrine pathology and pathobiology, neuroendocrine tumors, especially pheochromocytoma and paraganglioma
Seeing Patients In
Tufts Medical Center
800 Washington St.
Boston, MA 02111
Phone #: 617-636-5829
Fax #: 617-636-8302
2021, "Top Doctor", Boston Magazine
2021, Lead author or contributing author to multiple chapters in World Health Organization bluebooks on Endocrine, Pediatric and Head and Neck tumors. In progress
2020, Chair of the Dataset Authoring Committee of the International Committee for Cancer Reporting (ICCR), developing international guidelines for standardized pathology reporting of pheochromocytoma and paraganglioma.
2018/2019, "Top Doctor," Boston Magazine
2017, "Top Doctor," Boston Magazine
2015, "Top Doctor," Boston Magazine
2011, Science Award, Pheo Para Alliance
Past-president of Endocrine Pathology Society
Former Editor-in-Chief of Endocrine Pathology
Thompson LDR, Gill AJ, Asa SL, Clifton-Bligh RJ, de Krijger RR, Kimura N, Komminoth P, Lack EE, Lenders JWM, Lloyd RV, Papathomas TG, Sadow PM, Tischler AS. Dataset for the Reporting of Pheochromocytoma and Paraganglioma: Explanations and Recommendations of the Guidelines from the International Collaboration on Cancer Reporting (ICCR). Hum Pathol. 2020, 32407815
Grubbs EG, Lechan RM, Edeiken-Monroe B, Cote GJ, Trotter C, Tischler AS & Gagel RF 2020 Early thyroidectomy in multiple endocrine neoplasia: a four decade experience. Endocr Relat Cancer. 32464600
Pacak K, Eisenhofer G & Tischler AS 2020 Phaeochromocytoma - advances through science, collaboration and spreading the word. Nature Rev Endocrinol 16 621-622. (Commentary) 32934348
Powers JF, Cochran B, Baleja JD, Sikes HD, Pattison AD, Zhang X, Lomakin I, Shepard-Barry A, Pacak K, Moon SJ, et al. 2020 A xenograft and cell line model of SDH-deficient pheochromocytoma derived from Sdhb+/- rats. Endocr Relat Cancer 27 337-354. 32252027
Papathomas TG, Suurd DPD, Pacak K, Tischler AS, Vriens MR, Lam AK & de Krijger RR 2021 What Have We Learned from Molecular Biology of Paragangliomas and Pheochromocytomas? Endocr Pathol. 33433885
Pacak K, Jochmanova I, Prodanov T, Yang C, Merino MJ, Fojo T, et al. New Syndrome of Paraganglioma and Somatostatinoma Associated With Polycythemia. J Clin Oncol. 2013;31:1690-8.
Chae YC, Angelin A, Lisanti S, Kossenkov AV, Speicher KD, Wang H, et al. Landscape of the mitochondrial Hsp90 metabolome in tumours. Nature Communications. 2013;4:2139.
Gimenez-Roqueplo AP, Tischler AS. Pheochromocytoma and Paraganglioma: progress on all fronts. Endocr Pathol. 2012;23:1-3.
Eisenhofer G, Tischler AS, de Krijger RR. Diagnostic tests and biomarkers for pheochromocytoma and extra-adrenal paraganglioma: from routine laboratory methods to disease stratification. Endocr Pathol. 2012;23:4-14.
Neuroendocrine Tumor Research Foundation A phenotypically correct model for SDHB-mutated Pheochromocytoma/Paraganglioma November 2020
Arthur Tischler is a surgical pathologist at Tufts Medical Center and professor of pathology at Tufts University School of Medicine. His research deals with catecholamine-producing adrenal gland neuroendocrine tumors called pheochromocytomas and their extra-adrenal counterparts known as paragangliomas. It encompasses basic and translational aspects of pheochromocytoma biology, with a particular focus on development and application of models for basic and pre-clinical research. Dr Tischler established the widely utilized PC12 rat pheochromocytoma line in a collaborative study with Dr Lloyd Greene in 1976. More recently, mouse pheochromocytoma (MPC) cell lines now used for testing a variety of pre-clinical imaging and treatment modalities were developed in the Tischler laboratory at Tufts Medical Center by Dr. James Powers and Dr. Tischler. Current efforts in the laboratory are focused on developing animal models specifically relevant to often-malignant hereditary pheochromocytomas and paragangliomas caused by mutations of succinate dehydrogenase genes and on establishing human pheochromocytoma/paraganglioma cell lines, which currently do not exist. Dr. Tischler has served as Editor in Chief of the journal Endocrine Pathology and as president of the Endocrine Pathology Society. He was a founding member of the Pheochromocytoma Research and Support Organization (PRESSOR) and currently co-chairs the PRESSOR Tumor Models Working Group. In 2011 he received the annual Science Award from the PheoPara Alliance, a patient advocacy organization supporting research and education of both patients and clinicians.
US and Canadian Academy of Pathology
New England Society of Pathologists
American Association for the Advancement of Science, Endocrine Pathology Society