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Lesley A. Inker, MD, MS Accepting New Patients Virtual Appointments Available

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Programs + Specialties
Training + Education McMaster School of Medicine, Hamilton, Ontario; McMaster University Hospitals; University of British Columbia, Vancouver; Tufts Medical Center
Board Certifications Internal Medicine, Nephrology
NPI # 1659482743
Gender Female
Language(s) Hebrew
Accepted Insurances View Accepted Insurances at Tufts Medical Center

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Tufts Medical Center
4th Floor
35 Kneeland St.
Box 391
Boston, MA 02111
Phone #: 617-636-5866
Fax #: 617-636-2369

2022, Clinical Research Forum Distinguished Clinical Research Achievement Award
2022, "Top Doctor", Boston Magazine
2021, "Top Doctor", Boston Magazine
2020, "Top Doctor," Boston Magazine
2020, ASN Distinguished Researcher Award
2018/2019, "Top Doctor," Boston Magazine
2018, Garabed Eknoyan Award from National Kidney Foundation
2017, "Top Doctor," Boston Magazine
2000, Second and Third Prizes in Oral Presentation Category, Annual Resident Research Day, McMaster University
1999, Best Oral Presentation, South-West Ontario Critical Care Conference, London Ontario
1998, First Prize in Case Report Category, Annual Res

View a full list of Dr. Inker's publications here.

Boston Magazine Top Doctors 2023

2023 “Top Doctors” at Tufts Medical Center

See our Top Doctors
Boston Magazine 2022 Top Doctors

2022 “Top Doctors” at Tufts Medical Center

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Top Doctor 2021

2021 “Top Doctors” at Tufts Medical Center

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Top Doctors Boston Magazine 2020

2020 “Top Doctors” at Tufts Medical Center

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In the News Graphic

Alport syndrome expert appointed to Medical Advisory Committee

Learn more about the Alport Syndrome Foundation and the committee
Boston Magazine 'Top Doctor' Award 2016

Boston magazine honors 2016 “Top Doctors” at Tufts Medical Center.

2016 Boston magazine Top Doctors
Hannah Lee, MD and a co-worker in gastroenterology reviewing a patient chart at Tufts Medical Center in Boston.

Making medical decisions more personal: Studying populations that are likely to benefit from health care.

Making medical decisions more personal

Therapeutics to slow kidney dysfunction

Learn more about the trial
Boston Magazine 'Top Doctor' Award 2017

Boston Magazine honors 2017 “Top Doctors” at Tufts Medical Center.

2017 Boston Magazine Top Doctors
Dr. Clarissa Yang on the cover of 2019 Boston Magazine Top Doctor issue.

2019 “Top Doctors” at Tufts MC and Tufts Medical Center

See our Top Doctors

Dr. Inker's clinical interests are general nephrology, detection and treatment of CKD, assessment of kidney function, geriatric nephrology, HIV-associated kidney disease, and kidney stones. She is the Director for Quality Improvement for the Division, Director of the Kidney and Blood Pressure Center and director of the Kidney Function Evaluation Clinic

Dr. Inker’s primary research interests are in epidemiology and outcomes related to CKD. Her major research interest is in the estimation ad measurement of glomerular filtration rate (GFR). She was the co-principal investigator of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), a collaborative effort to use pooled individual patient data to address central questions in the epidemiology of CKD, including developing improved glomerular filtration rate (GFR) estimation equations, using these equations to refine prevalence estimates for CKD from National Health and Nutrition Examination Survey. The principle outcomes of this work are new estimating equations for GFR the CKD-EPI creatinine equation, the CKD-EPI cysatin C equation and the CKD-EPI creatinine-cystatin C equation. All of these are more accurate than the currently most commonly used equation, the MDRD Study equation. The creatinine-cystatin C equation is more precise than either the CKD-EPI creatinine or the CKD-EPI cystatin C equation. More recently, she is investigating novel filtration markers, including low molecular weight proteins, beta trace protein and beta-2-microglobulin. dR Inker has led or collaborated in several research studies to evaluate kidney function in other populations, including HIV positive people, elderly, patients with severe liver disease and cancer. She is now an investigator in the NIDDK CKD-Biomarker Consortium, a collaborative effort to discover and validate new markers for CKD.

Another major research interest is investigation of alternative endpoints for kidney disease outcomes in clinical trials, including changes in urine protein and lesser declines in GFR compared to the currently accepted doubling of serum creatinine.

Policy - Guideline Development and Implementation
Dr. Inker is also interested in research and policy related to implementation of CKD Guidelines. She works with NKF leadership and national organizations to implement CKD guidelines, including issues related to GFR estimation and revisions to diagnostic codes for kidney disease.

Chair, Steering Committee NKF Patient Network
Alport Syndrome Foundation Medical Advisory Council
National Kidney Foundation
Clinical Oversight committee, co-chair, Kidney Early Education Program (KEEP)
International Renal Work Group for revisions to the International Classification of Disease - 11th edition. Co-chair
Member, scientific advisory board, National Kidney Foundation
Member, National Kidney Disease Education Program