Lester Y. Leung, MD, MSc Accepting New Patients Virtual Appointments Available

Programs + Specialties	Neurology Stroke Center
Training + Education	Tulane University School of Medicine; Beth Israel Deaconess Medical Center; Boston Medical Center
Board Certifications	Neurology, Vascular Neurology
NPI #	1396060141
Gender	Male
Accepted Insurances	View Accepted Insurances at Tufts Medical Center

Loading ... Loading ...

Tufts Medical Center Biewend Building 260 Tremont Street Box 314 Boston , MA  02111 Phone #: 617-636-4948 Fax #: 617-636-8199 Map It

2016, Lester Adelman Tufts Neurology Residency Teaching Award
2014, Outstanding Resident-Fellow Teaching Award, Beth Israel Deaconess Medical Center
2010, Leon A. Weisberg, M.D. Memorial Award
2009, Gold Humanism in Medicine Honor Society
2009, Alpha Omega Alpha Honor Medical Society

1. Leung LY, Tian D, Brangwynne CP, Weitz DA, Tschumperlin DJ. A new microrheometric approach reveals individual and cooperative roles for TGF-1beta and IL-1beta in fibroblast-mediated stiffening of collagen gels. FASEB J. 2007 Jul;21(9):2064-73. PMID: 17341683.

2. Looze C, Yui D, Leung LY, Ingham M, Kaler M, Yao X, et al. Proteomic profiling of human plasma exosomes identifies PPAR-gamma as an exosome-associated protein. Biochem Biophys Res Commun. 2009 Jan 16;378(3):433-38. PMID: 19028452. PMCID: PMC2633355.

3. Leung LY, Albright KC, Boehme AK, Tarsia J, Shah KR, Siegler JE, et al. Short-term Bleeding Events Observed with Clopidogrel Loading in Acute Ischemic Stroke Patients. J Stroke Cerebrovasc Dis. 2013 Oct;22(7):1184-89. PMID: 23541421. PMCID: PMC4447207.

4. Bernson-Leung ME and Leung LY, Kumar S. Synthetic Cannabis and Acute Ischemic Stroke. J Stroke Cerebrovasc Dis. 2014 May-Jun;23(5):1239-41. PMID: 24119618.

5. Krishnan V, Leung LY, Caplan LR. A Neurologist’s Approach to Delirium: Diagnosis and Management of Toxic Metabolic Encephalopathies. Eur J Int Med. 2014 Feb;25(2):112-16. PMID: 24332366.

6. Leung LY, Caplan LR. Factors associated with delay in presentation to the hospital for young adults with ischemic stroke. Cerebrovasc Diseases. 2016;42(1-2):10-14. PMID: 26953591.

7. Rai S, Thaler DE, Salehi P, Madan N, Leung LY. More to atherosclerosis than stenosis: symptomatic carotid artery with intraplaque hemorrhage. Stroke. 2017 Apr;48(4):e104-e107. PMID: 28292865.

8. Leung LY, McAllister ML, Selim M, Fisher M. Factors influencing oral anticoagulant prescribing for atrial fibrillation. J Stroke. 2017 May;19(2):232-235. PMID: 28460492. PMCID: PMC5466293.

9. Leung LY, Bartz TM, Rice K, Floyd J, Pstay B, Gurierrez J, et al. Blood pressure and heart rate measures associated with increased risk of covert brain infarction and worsening white matter in older adults. Arterioscler Thromb Vasc Biol. 2017 Aug;37(8):1579-1586. PMID: 28663254. PMCID: PMC5551454.

10. Leung LY, Melkumova E, Thaler DE. Longitudinal care for young adults with stroke. JAMA Neurol. 2017 Oct1;74(10):1163-1164. PMID: 28828467.

11. Smith EE, Kent DM, Bulsara KR, Leung LY, Lichtman JH, Reeves MJ, Towfighi A, Whiteley WN, Zahuranec DB; American Heart Association Stroke Council.. Effect of Dysphagia Screening Strategies on Clinical Outcomes After Stroke: A Systematic Review for the 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke. Stroke. 2018;49(3):e123-e128. PMID: 29367332.

12. Smith EE, Kent DM, Bulsara KR, Leung LY, Lichtman JH, Reeves MJ, Towfighi A, Whiteley WN, Zahuranec DB; American Heart Association Stroke Council. Accuracy of Prediction Instruments for Diagnosing Large Vessel Occlusion in Individuals With Suspected Stroke: A Systematic Review for the 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke. Stroke. 2018;49(3):e111-e122. PMID: 29367333.

13. Leung LY, Han PKJ, Lundquist C, Weinstein G, Thaler DE, Kent D. Clinicians’ perspectives on incidentally discovered silent brain infarction – a qualitative study. PLoS One. 2018;13(3):e0194971. PMID: 29596459.

14. Johnston SC, Easton JD, Farrant M, Barsan W, Conwit RA, Elm JJ, et al.; Clinical Research Collaboration, Neurological Emergencies Treatment Trials Network, and the POINT Investigators. Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA. N Engl J Med. 2018;379(3):215-225. PMID: 29766750.

15. Leung LY, Han PKJ, Lundquist C, Weinstein G, Thaler DE, Kent D. Patients’ perspectives on incidentally discovered silent brain infarction – a qualitative study. J Patient Rep Outcomes. 2019;3(1):23. PMID: 30982930. PMCID: PMC6462438.

16. Fu S, Leung LY, Wang Y, Raulli AO, Kallmes DF, Kinsman KA, et al. Natural language processing for the identification of silent brain infarcts from neuroimaging reports. JMIR Med Inform. 2019;7(2):e12109. PMID: 31066686.

17. Johnston KC, Bruno A, Pauls Q, Hall CE, Barrett KM, Barsan W, et al.; Neurology Emergencies Treatment Trials Network and the SHINE trial investigators. Intensive vs standard treatment of hyperglycemia and functional outcome in patients with acute ischemic stroke: the SHINE randomized clinical trial. JAMA. 2019;322(4):326-335. PMID: 31334795.

18. McCarty J, Leung L, Peterson R, Sitton C, Sarraj A, Riascos R, Brinjikj W. Ischemic Infarction in Young Adults: A Review for Radiologists. Radiographics. 2019;39(6). 1629-1648. PMID: 31589580.

19. Ridha M, Malek A, Arkun K, Leung LY. The utility of histopathologic characteristics of thrombi in large vessel occlusions. Neurol Clin Pract. 2019;9(6). PMID: 32042484.

20. Kalani R, Bartz TM, Suchy-Dicey A, Elkin MSV, Psaty BM, Leung LY, et al. Cholesterol variability and cranial magnetic resonance imaging findings in older adults: the Cardiovascular Health Study. Stroke. 2020;51(1):69-74. PMID: 31842691.

21. Fu S, Leung LY, Raullio A-O, Kallmes DF, Kinsman KA, Nelson KB, et al. Assessment of the impact of EHR heterogeneity for clinical research through a case study of silent brain infarction. BMC Med Inform Decis Mak. 2020;20:60. PMID: 32228556.

22. Huggins HE, Brady M, Thaler DE, Leung LY. Differences in presenting symptoms of acute stroke among young and older adults. J Stroke Cerebrovasc Dis. 2020;29:104871. PMID: 32689591.

23. Dmytriw AA, Phan K, Schirmer C, Settecase F, Heran MKS, Efendizade A, et al. Ischaemic stroke associated with COVID-19 and racial outcome disparity in North America. Journal of Neurology, Neurosurgery, and Psychiatry. 2020 Dec;91(12):1362-1364. PMID: 32801118.

24. Carneiro T, Dashkoff J, Leung LY, Nobleza COHS, Marulanda-Londono E, Hathidara M, et al. Intravenous tPA for Acute Ischemic Stroke in Patients with COVID-19. J Stroke Cerebrovasc Dis. 2020;29(11):105201. PMID: 33066885.

25. Gans S, Michaels E, Thaler DE, Leung LY. Detection of symptoms of late complications after stroke in young survivors with active surveillance versus usual care. Disabil Rehabil. 2021 Feb 19;1-5. PMID: 33065166.

26. Nogueira RG, Qureshi MM, Abdalkader M, Martins SO, Yamagami H, Qiu Z, et al. Global impact of COVID-19 on stroke care and IV thrombolysis. Neurology. 2021 Jun 8;96(23):e2824-e2838. PMID: 337566997.

27. Nogueira RG, Abdalkader M, Qureshi MM, Frankel MR, Mansour OY, Yamagami H, et al. Global impact of COVID-19 on stroke care. Int J Stroke. 2021 Mar 29: online ahead of print. PMID 33459583.

28. Koh MH, Yen SC, Leung LY, Gans S, Sullivan K, Adibnia Y, Pavel M, Hasson CJ. Exploiting telerobotics for sensorimotor rehabilitation: a locomotor embodiment. J Neuroeng Rehabil. 2021;18(1):66.

29. Leung LY, Fu S, Luetmer PH, Kallmes DF, Madan N, Weinstein G, Lehman VT, Rydberg CH, Nelson J, Liu H, Kent DM. Agreement between neuroimages and routinely-obtained neuroimaging reports for artificial intelligence (AI)-based detection of silent brain infarcts and white matter disease. BMC Neurol. 2021 May 11;21(1):189: PMID: 33975556.

30. Brown DL, Levine DA, Albright K, Kapral MK, Leung LY, et al. Benefits and risks of dual versus antiplatelet therapy for secondary stroke prevention: a systematic review for the 2021 guideline for the prevention of stroke in patients with stroke and transient ischemic attack. Stroke. 2021 May 24: online ahead of print. PMID: 34024115.

31. Dmytriw AA, Dibas M, Schirmer CM, Settecase F, Heran MKS, Efendizade A, et al. Age and acute ischemic stroke outcome in North American patients with COVID-19. J Am Heart Assoc. 2021 Jul 3:e021046, online ahead of print. PMID: 34219466.

32. Kent DM, Leung LY, Zhou Y, Luetmer PH, Kallmes DF, Nelson JN, et al. Association of silent cerebrovascular disease identified using natural language processing and future ischemic stroke. Neurology. 2021 Sep 28;97(13):e1313-1321. PMID: 34376505.

33. Leung LY, Zhou Y, Fu S, Zheng C, Luetmer P, Kallmes DF, et al. Risk factors for silent brain infarcts and white matter disease in a real-world cohort identified by NLP. Mayo Clinic Proceedings. 2022;97(6):1114-1122. PMID: 35487789.

34. Wang AY, Leung LY, Puttock EJ, Luetmer PH, Kallmes DF, Nelson J, et al. Stratifying future stroke risk with incidentally discovered white matter disease severity and covert brain infarct site. Cerebrovasc Dis. 2022 Jun 27:1-5. PMID: 35760063.

35. Kent DM, Leung LY, Puttock EJ, Wang AY, Luetmer PH, Kallmes DF, et al. Development of Parkinson’s disease and its relationship with incidentally-discovered white matter disease and covert brain infarction in a real-world cohort. Ann Neurol. 2022 Jul 22. PMID: 35866711.

36. Kent DM, Leung LY, Zhou Y, Luetmer PH, Kallmes DF, Nelson J, et al. Association of incidentally discovered covert cerebrovascular disease identified using natural language processing and future dementia. J AM Heart Assoc. 2023 Jan 3;12(1):e027672. PMID: 36565208.

Lester Y. Leung, MD, MSc is a vascular neurologist (stroke specialist), clinical investigator, and medical educator. He is the Director of the Comprehensive Stroke Center at Tufts Medical Center and the Founder and Director of the Stroke and Young Adults (SAYA) Program. He is interested in improving prehospital identification and management of stroke, addressing disparities in stroke care, and improving the care and post-stroke outcomes of young adults with stroke.

American Academy of Neurology
American Heart Association/American Stroke Association
Massachusetts Medical Society

Interview with Lester Leung, MD,MSc Director Comprehensive Stroke Center Tufts Medical Center (AUDIO)

Listen now

Lester Leung, MD talks about patient needs at center of stroke care debate

Lester Leung, MD talks about patient needs at center of stroke care debate - Read More

Caring for stroke patients

Learn about our promise

Tufts MC certified as an advanced comprehensive stroke center

Learn more about this accreditation

Lester Leung, MD tells us about stroke risks that are especially important for young women to know

Read how migraines and contraceptives can lead to stroke

Paul’s Story: Recovering from stroke, one step at a time

Learn more about Paul's journey back to health

Mayra’s story: Surviving stroke, managing motherhood

Read about Mayra's stroke and OB care at Tufts MC

Lester Y. Leung, MD named Director of the Comprehensive Stroke Center at Tufts MC.

Meet Dr. Leung

Working Together: New Program a Stroke of Genius for Young Adults

Read about Dr. Leung

Boston Magazine: Stroke - Not Just for 55+: How Dr. Lester Y. Leung says we can help young adults move forward.

Boston Magazine shares information about stroke in young adults

Time is brain: Recognize the signs of a stroke and take action quickly - every minute counts.

Know the signs

When Stroke Strikes Early In Life

Learn about the SAYA program

What are the common stroke symptoms in young adults? Lester Leung, MD addresses this question and more in an interview with YourHealthRadio.org.

Listen to the interview