For a complete list of Dr. Catalano's publications, see here
NATIONAL AND INTERNATIONAL PRESENTATIONS
"Managing Gestational Diabetes: Does Diabetes Beget Diabetes?" 21st Annual Diabetes Conference – Individualizing Diabetes Care: Targets and Treatment, March 7, 2020, Rochester, NY.
"Gestational Diabetes: a Metabolic Stress Test and Harbinger of Future Metabolic Dysfunction." Eunice Kennedy Shriver National Institute of Child Health and Human Development, May 19-20, 2020, Bethesda, MD. (Virtual Presentation)
"Maternal Obesity and Gestational Diabetes: Short and Long-term Effects on the Offspring." Yale Endocrine Grand Rounds May 28, 2020 New Haven, CT. (Virtual Presentation)
"Obesity and Pregnancy." Columbia University, August 28, 2020, New York, NY. (Virtual Presentation)
"Interaction Among Maternal Metabolism, Fetal Sex and Neonatal Growth Outcomes." Skajaa GO, O'Tierney-Ginn PF, Presley L, Minium J, Catalano PM, Oral Presentation September 4, 2020. (Virtual Presentation)
"20 years HAPO study: What have we learned so far?" European Association for the study of Diabetes 56th EASD Annual Meeting September 21-25, 2020. (Virtual Presentation)
"Short and Long-term Effects of Obesity and Excessive Gestational Weight Gain in Women and their Children." IADPSG, November 13-15, 2020, Kyoto, Japan. (Virtual Presentation)
Patrick Catalano MD is a Professor and Vice Chair of Obstetrics and Gynecology at Tufts University School of Medicine and a Maternal -Fetal Medicine specialist at Tufts University Medical Center. His research is focused on maternal metabolism in women whose pregnancies are complicated by diabetes and obesity. Further he is studying the short and long-term effects on mothers and their children. He has had continuous funding from the Eunice Kennedy Shriver National Institutes of Child Health and Human Development for the past 30 years.
The Impact of Lifestyle Interventions Prior to Pregnancy on Maternal and Neonatal Adipocyte Metabolism
The goal of this grant is to investigate the longitudinal effects of pregravid lifestyle interventions on maternal at metabolic function and neonatal adiposity and examine potential early biomarkers and mechanisms as predictors of long-term metabolic outcomes in the offspring.
NIH/NIDDK U01 DK123795-01
Measuring Early Pregnancy Glycemia and Its Impact on Adverse Outcomes
The objective of this proposal is a prospective observational study to examine glucose physiology during pregnancy.
Obesogenic Origins of Maternal and Child Metabolic Health Involving Dolutegravir (ORCHID)
The overall purpose of this grant is to understand how dolutegravir (DTG) use during pregnancy affects the metabolic health of women and their children.
Tufts Institute for Global Obesity Research (TIGOR)
Determine the longitudinal metabolomic profile of overweight and obese women undergoing lifestyle interventions to decrease weight before and during pregnancy and delivery.
Tufts-IRACDA NIGMS, K12GM133314
The impact of lifestyle interventions prior to pregnancy on maternal and neonatal adipocyte metabolism
The goal of the project is to determine how maternal adipose tissue function and neonatal stem cell metabolism improve after pregravid lifestyle intervention, with the purpose of examining potential biomarkers as predictors of long-term metabolic health in the offspring.
2019 – 2024
Blood Levels of Glycated CD59, a Novel Biomarker to Assess Pregnancy-induced Glucose Intolerance.
The overall goal of this proposal is to continue studies on plasma glycated CD59 (pGCD59) as a novel biomarker for gestational diabetes mellitus (GDM). Human studies indicate that pGCD59 is a sensitive biomarker of pregnancy-induced glucose intolerance1and is a molecular link between glycation inactivation of CD59 and the complications of GDM.
2019 – 2024
Kisspeptin: A novel Regulator of Insulin sensitivity in Pregnancy.
The goal of this project is to provide a comprehensive five-year training program for mentored career development in patient-oriented research for the PI, including independent clinical trials, specifically constructed to provide focused training pregnancy physiology and in the mechanisms of insulin physiology
Tufts Collaborative Grant
2019 – 2020
Infant feeding and early childhood adiposity: identifying targets for future intervention.
The overall goal is to investigate the relationship between maternal BMI, maternal infant feeding style and infant adiposity and to examine mediators or moderators of the maternal infant feeding style and infant adiposity relationship.
NIH/NICHD R01 HD091054
Placental Lipid Metabolism Impacts Fetal Adiposity and is Programmed by the Maternal Metabolic Milieu in Early Pregnancy.
Goals: To determine how maternal fat metabolism in early pregnancy programs placental lipid metabolism and neonatal fat deposition.
Level and Timing of Diabetic Hyperglycemia in utero: The Transgenerational Effect on Adult Morbidity (TEAM Study).
The objective of this proposal is to combine data from research conducted on a cohort of women with pregestational diabetes and follow-up of their offspring to elucidate the effect of exposure to hyperglycemia in utero on a spectrum of metabolic diseases and cardiovascular dysfunction.
NIH/NICHD R01 HD091735
Placental miRNA Profiles Associated with Maternal Insulin Resistance and Fetal Adiposity: Maternal-Placental Crosstalk.
Goals: To determine the association between miRNA originating in the placenta with maternal insulin resistance and fetal adiposity.
NIH/NICHD NIH HD 088061-01A1
Lifestyle Intervention in Preparation for Pregnancy. Click to view grant
The objective of this project is to break the vicious cycle of obesity/metabolic dysfunction during pregnancy to decrease the risk of maternal and neonatal perinatal morbidity. The primary aim is to decrease adiposity at birth in infants of overweight/obese women through lifestyle intervention of behavioral modification, healthy eating and exercise before a planned pregnancy using a RCT in women after their first pregnancy.
Role: Principal Investigator
NIH/NICHD NIH HD 079647
Comparison of Two Screening Strategies for Gestational Diabetes. The study will examine the current ACOG and IADPSG screening strategies for the diagnosis of gestational diabetes based on clinical outcomes. Outcomes include if either screening and treatment strategy results in healthier infants and mothers.
NIH/NIDDK NIH R8S119091
Hyperglycemia and Adverse Pregnancy Outcome-Follow up Study (HAPO-FUS).
The HAPO-FUS will evaluate the mothers who participated in the original HAPO study and their offspring at 8-12 years of age.
The purpose of the study is to evaluate maternal obesity and glucose tolerance during pregnancy as risk factors for metabolic dysfunction in the mother and her offspring.
Role: Principal Investigator at the MetroHealth site/Vice Chair Executive Committee
Past Grants Download PDF