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Effects of BCR-ABL tyrosine kinase inhibitors on platelets and white blood cells

Effects of BCR-ABL tyrosine kinase inhibitors on platelets and white blood cells

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All genders
person-wave 18+
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Overview

Principal Investigator: Iris Jaffe

We are interested in the side effects of medications commonly used to treat diseases like chronic myelogenous leukemia. In particular, we are interested in the effects on blood vessel cells, white blood cells, and platelets. Our data will allow us to determine any effects that these medications have on human white blood cells and platelets.

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Richard Travers

Study details

Inclusion Criteria
  • 1. Healthy, non-pregnant adults over the age of 18
  • 2. Weigh at least 110 pounds
  • 3. Not currently taking anti-platelet therapy
Exclusion Criteria
  • 1. Subjects currently on anti-platelet therapy and/or who have taken anti-platelet medications within the last 14 days.
  • 2. Evidence of poor venous access, or the inability to have blood drawn
Study Requirements

You will be asked to give a sample of blood (2-4 teaspoons) to be used in research experiments that same day collected from a vein in your arm. The blood will be collected and then platelets and white blood cells will be isolated for research.

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