This study is designed to test a potential biomarker to identify NCP patients. A biomarker is a characteristic that is unique to NCP patients and will help to identify them from DED patients so that correct treatment can be provided to them.
R33
Prospective study to validate the imaging biomarker for neuropathic corneal pain
Dry eyes
All genders
18+
Recruiting now
Overview
Principal Investigator: Pedram Hamrah, MD
Contact Us
Ophthalmology Coordinator
Study details
Inclusion Criteria
- Dry Eye Disease (DED) Group: complaint of ocular surface discomfort or dry eye disease; symptoms lasting at least 3 months; presence of 2 markers (Anesthetized Schirmer's score <10mm; corneal staining of >3/15; or Tear breakup time <10 seconds)
- Neuropathic Corneal Pain (NCP) Group: complaint of ocular surface discomfort or dry eye disease; symptoms lasting at least 3 months; presence of 2 markers (Anesthetized Schirmer's score >10mm; corneal staining of 10 seconds)
- Control Group: No symptoms of ocular surface discomfort or dry eye disease; All in the following of both eyes:Anesthetized Schirmer's score >10mm; corneal staining of 10 seconds); the same sex and within 5 years of age of a patient in the NCP group
Exclusion Criteria
- Pregnant or nursing
- Irregular corneal disease
- Ocular surgery or infection in the past 3 months
Study Requirements