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MelroseWakefield Hospital has been the healthcare partner families trust on the good days, and challenging ones since 1893. We’re on a mission to empower people to live their best lives by providing exceptional care locally. Whether you need expert cardiac care, 24-hour emergency services, complex surgery or family-focused maternity services, you can trust in MelroseWakefield.
About MelroseWakefield Hospital
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Join us and take advantage of our wide range of classes, seminars, events and groups that are designed specifically to promote healthier living throughout the community.
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We’re here to help you and your family get and stay healthy. Whether you’re looking to schedule an appointment, get answers about your bill or explore treatment options in your community, we’ll point you in the right direction.

clinical trial
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This is a multi-center first-in-human, Phase 1, open-label, dose ranging study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and efficacy of single ascending doses of SBT777101 administered intravenously (IV) in subjects with active rheumatoid arthritis (RA) and an inadequate response to at least 2 prior biologic or targeted synthetic disease modifying anti-rheumatic drug (b/tsDMARD) therapies with different mechanisms of action.
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This trial will help to determine if either the experimental arm (adjuvant reirradiation plus pembrolizumab, followed by pembrolizumab to complete 12 months total of pembrolizumab and/or pembrolizumab alone for 12 months) significantly improves Overall Survival (OS) compared to adjuvant reirradiation plus concurrent platinum chemotherapy in high risk patients.
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This is a phase I trial to see whether patients are able to adhere to a modified, high fat/low carbohydrate diet (the sHFLC + KetoPhyt Diet) with a supplement named KetoPhyt that includes ketones and anti-inflammatory properties.

The classic ketogenic diet (KD) is difficult for patients to adhere to due to its stringent nature. A modified KD has been developed that mimics the glucose lowering, ketone raising effects and the anti-cancer outcomes of the KD.
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This phase II trial tests how well an imaging procedure called fludeoxyglucose F-18 (FDG) positron emission tomography/computed tomography (PET/CT) works in predicting response to standard of care chemotherapy prior to surgery in patients with HER2-positive stage IIa-IIIc breast cancer. FDG is a radioactive tracer that is given in a vein before PET/CT imaging and helps to identify areas of active cancer. PET and CT are imaging techniques that make detailed, computerized pictures of areas inside the body.
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Our principal investigators and trainees have received a number of honors and awards for their leadership and accomplishments in research that advances the understanding of preterm birth and its complications, maternal obesity and fetal and neonatal genomic medicine. We are grateful for the recognition from our peers and the honors bestowed on us by international and national associations and institutions for our contributions.
Publications + Awards
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The faculty and team of the Institute for Clinical Research and Health Policy Studies (ICRHPS) at Tufts Medical Center regularly present their research in articles published in the world’s most prestigious, peer-reviewed journals and by the Agency for Healthcare Research and Quality.