Search Tufts Medicine

Displaying 1 - 20 of 71
page
...
The mission of the Cardiac Biology Research Center (CBRC) is to advance our understanding of fundamental mechanisms that regulate cardiac structure and function across multiple disease conditions, including heart failure, acute myocardial infarction, pulmonary and systemic hypertension, hypertrophic cardiomyopathy, autonomic dysfunction and arrhythmias. With advanced expertise in molecular cardiology, integrative physiology, molecular imaging, nanotechnology, biomedical engineering, and translational research, the CBRC studies novel signaling mechanisms that govern cardiomyocyte and non-myocyte cell populations.
clinical trial
...

This is a prospective, multicenter, randomized, double-blind, placebo-controlled, parallel-group, large simple trial to investigate the efficacy and safety of a single intravenous (IV) infusion of BE1116 in patients with traumatic injury and confirmed or suspected acute major bleeding predicted to receive a large volume blood product transfusion. Randomization will be in a 1:1 ratio (BE1116:placebo) and stratified by study site. Subjects will receive a single IV infusion of either BE1116 or placebo, in addition to the study site's standard resuscitation methods and protocol.
page
...
We are committed to providing exceptional care and injury prevention for children. Our mission goes beyond treating injuries so we develop innovative injury prevention programs for children. Through our community safety programs, we have already reached out to over 33,000 children and their families in New England alone.
page
...
The Chen lab develops novel imaging methods to understand mechanisms of cardiovascular disease, to image disease as it progresses and to improve cardiovascular outcomes by targeting or monitoring therapies using molecular imaging. He is applying these novel technologies to heart failure and cardio-oncology.