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Patient Stories
February 21, 2021
After enjoying a day of golf with his friends, Stanley Coolen began experiencing an upset stomach. Stanley is an active, healthy 72-year old from Saugus, MA. According to him, neither he nor his wife, Nicky, had been sick for a day in the nearly 50 years they had been married. But as he approached the clubhouse, he collapsed in cardiac arrest.
Patient Stories
January 29, 2019
It was April 8, 2018, and Dana Corr was looking forward to celebrating his 55th birthday that day with his wife and two daughters in their Westford home. He had just returned from a trip visiting colleges in Rhode Island the day before with his daughter. Unfortunately, all celebrations were put on hold that day as his heart seemed to have other plans.
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MCRI is comprised of 12 scientists dedicated to investigating the molecular mechanisms of common cardiovascular diseases and translating those discoveries into new clinical strategies for diagnosis and therapy to prevent and treat heart diseases including heart attack, high blood pressure and heart failure.
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The Molecular Cardiology Research Institute (MCRI) at Tufts Medical Center is dedicated to investigating the molecular mechanisms of common cardiovascular diseases and translating those discoveries into new clinical strategies for diagnosis and therapy to prevent and treat various forms of heart disease including heart attack, high blood pressure and heart failure.
Molecular Cardiology Research Institute (MCRI)
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The mission of the Cardiac Biology Research Center (CBRC) is to advance our understanding of fundamental mechanisms that regulate cardiac structure and function across multiple disease conditions, including heart failure, acute myocardial infarction, pulmonary and systemic hypertension, hypertrophic cardiomyopathy, autonomic dysfunction and arrhythmias. With advanced expertise in molecular cardiology, integrative physiology, molecular imaging, nanotechnology, biomedical engineering, and translational research, the CBRC studies novel signaling mechanisms that govern cardiomyocyte and non-myocyte cell populations.
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The Galper Lab has a long-standing interest in autonomic control of the heart and more recently in the pathogenesis of lethal ventricular arrhythmias following myocardial infarction in mouse models for type II diabetes and metabolic syndrome. We also have an interest in the mechanism of atrial fibrillation in these mouse models for metabolic heart disease.
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The Kapur Lab focuses on molecular mechanisms of cardiac remodeling and myocardial recovery. The laboratory has generated novel insight into signaling via the transforming growth factor beta (TGFb) family with a particular focus on the TGFb co-receptor endoglin (CD105) and Bone Morphogenetic Protein 9 (BMP9). The lab’s translational research focuses on preclinical models of acute and chronic heart failure, invasive hemodynamics, circulatory support device development, and cardioprotective mechanisms in the setting of acute myocardial infarction.
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The core focus of the Pulakat lab is the elucidation and manipulation of various biological pathways that contribute to the development and pathogenesis of cardio-metabolic diseases and aging and uncovering markers of sex differences in heart disease.
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The Interventional Cardiology Fellowship Program at Tufts Medical Center in Boston is a 1-year advanced fellowship for cardiovascular specialists seeking interventional expertise.
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At Tufts Medical Center, we treat the whole family. Whether you’re welcoming a newborn into the world or preparing for surgery, we’re here to help you navigate all phases of the health and wellness journey.
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