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MCRI is comprised of 12 scientists dedicated to investigating the molecular mechanisms of common cardiovascular diseases and translating those discoveries into new clinical strategies for diagnosis and therapy to prevent and treat heart diseases including heart attack, high blood pressure and heart failure.
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The Molecular Cardiology Research Institute (MCRI) at Tufts Medical Center is dedicated to investigating the molecular mechanisms of common cardiovascular diseases and translating those discoveries into new clinical strategies for diagnosis and therapy to prevent and treat various forms of heart disease including heart attack, high blood pressure and heart failure.
Molecular Cardiology Research Institute (MCRI)
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The mission of the Cardiac Biology Research Center (CBRC) is to advance our understanding of fundamental mechanisms that regulate cardiac structure and function across multiple disease conditions, including heart failure, acute myocardial infarction, pulmonary and systemic hypertension, hypertrophic cardiomyopathy, autonomic dysfunction and arrhythmias. With advanced expertise in molecular cardiology, integrative physiology, molecular imaging, nanotechnology, biomedical engineering, and translational research, the CBRC studies novel signaling mechanisms that govern cardiomyocyte and non-myocyte cell populations.
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The Galper Lab has a long-standing interest in autonomic control of the heart and more recently in the pathogenesis of lethal ventricular arrhythmias following myocardial infarction in mouse models for type II diabetes and metabolic syndrome. We also have an interest in the mechanism of atrial fibrillation in these mouse models for metabolic heart disease.
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The Kapur Lab focuses on molecular mechanisms of cardiac remodeling and myocardial recovery. The laboratory has generated novel insight into signaling via the transforming growth factor beta (TGFb) family with a particular focus on the TGFb co-receptor endoglin (CD105) and Bone Morphogenetic Protein 9 (BMP9). The lab’s translational research focuses on preclinical models of acute and chronic heart failure, invasive hemodynamics, circulatory support device development, and cardioprotective mechanisms in the setting of acute myocardial infarction.
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The core focus of the Pulakat lab is the elucidation and manipulation of various biological pathways that contribute to the development and pathogenesis of cardio-metabolic diseases and aging and uncovering markers of sex differences in heart disease.
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The Interventional Cardiology Fellowship Program at Tufts Medical Center in Boston is a 1-year advanced fellowship for cardiovascular specialists seeking interventional expertise.
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At Tufts Medical Center, we treat the whole family. Whether you’re welcoming a newborn into the world or preparing for surgery, we’re here to help you navigate all phases of the health and wellness journey.
About Tufts Medical Center
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Your gift to Lowell General Hospital supports the same programs that provide your friends, family and neighbors with the healthcare they rely on and deserve.
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The Women’s CV Health Research Group brings together basic scientists from the Molecular Cardiology Research Institute (MCRI) with scientists, clinician investigators and population researchers from diverse Departments at Tufts Medical Center including Internal Medicine, the Mother Infant Research Institute (MIRI), Obstetrics and Gynecology, and Pediatrics with the Tufts Freidman School of Nutrition Science and Policy, Tufts University School of Medicine and School of Public Health, and the Human Nutrition Research Center on Aging (HNRCA) with common interests in studying the unique aspects of Women’s Cardiovascular Health.
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The Division of Geographic Medicine and Infectious Diseases faculty at Tufts Medical Center in downtown Boston is deeply committed to helping all of our fellows reach their career goals.
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The Jaffe laboratory is focused on understanding the molecular mechanisms by which blood vessels become dysfunctional to lead to common cardiovascular conditions, including heart attack, stroke, high blood pressure, in-stent restenosis, vein graft failure and heart failure. We are interested in understanding how traditional risk factors like aging, obesity, high blood pressure or high cholesterol, or new risk factors like novel cancer treatments, cause blood vessels to become diseased. We are also focused on understanding sex differences in how these cardiovascular diseases develop, in order to identify sex-specific precision medicine strategies.
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Employer-matched gifts double your giving impact. It’s your employer's way of helping you support organizations and causes that are important to you.
Employer-Matched Giving
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When Lowell General Hospital was founded in 1891, we opened our doors to the community as a welcoming place where patients always come first. That mission is at the heart of how we provide healthcare to all who come through our doors today.
About Lowell General Hospital
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The Vascular Biology Research Center (VBRC) investigators work to understand the molecular underpinnings of healthy blood vessel function and how dysfunction develops, which can lead to cardiovascular diseases including high blood pressure, heart attack and stroke.
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Did you know Tufts Medical Center is the oldest hospital in Boston? Tufts Medical Center was established as the Boston Dispensary and was the first operating medical center in New England- and the third in the United States. It was commissioned by Paul Revere
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In advance of your surgery at Tufts Medical Center, please follow these instructions:
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