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Mother Infant Research Institute (MIRI)

We conduct research to improve maternal and child health from preconception through childhood. Our research supports healthier moms and babies.
Tomoko Kaneko-Tarui, MD, PhD working in the MIRI (Mother Infant Research Institute) lab.

MIRI's research focus

Our research focuses on the lifelong consequences of the intimate and unique biological relationship between mother and baby during pregnancy.

Medical research has already established that events that occur at critical stages of human development in the womb influence the later occurrence of diabetes, heart disease, stroke, osteoporosis and inflammatory disorders, such as asthma, in both childhood and adulthood.

The in-utero environment profoundly influences the developing fetus, altering its gene expression and, therefore, affecting lifelong health. Pregnancy is also a “stress test” for later health problems in the mother, such as cardiovascular disease and diabetes. 

Learn more about the research focus areas at MIRI.

MIRI’s mission

Tufts Medical Center's Mother Infant Research Institute (MIRI) aims to enhance the lifelong health of mothers and babies by building, growing and training a community of collaborative researchers with a multidisciplinary perspective. Our holistic view of patients, their families and communities uniquely positions us to reduce inequities and improve health outcomes across generations.

MIRI’s vision

We believe in a future where every parent can make informed decisions for their and their children's long-term health through advanced diagnostics and personalized treatments.

MIRI's clinical trials

At MIRI, our physicians, scientists and researchers are devoting their careers to improving the health of pregnant women and their babies. Working with our colleagues at Tufts University, we use "bench to bedside" research to advance knowledge and make new treatments available in less time.

The MIRI offers both large and targeted trials to patients. Clinical trials in the MIRI usually fall into one of two categories:

  • Investigator-initiated clinical trials – researchers at the MIRI design research studies and apply to major federal institutions like the National Institutes of Health for funding to conduct the study.
  • Multi-center clinical trials – nationwide or international projects that hospitals and other groups around the world can join and enroll patients into.

If you are interested in participating in a clinical trial, our staff will assist you and your family every step of the way. We rigorously follow all federal regulations and requirements for conducting clinical trials. We also recruit patients and work directly with them and their families throughout the process.

Often, you or a family member may be unsure about deciding if you should enroll in a trial. We help you understand the options and give you all the information needed to make a well-informed decision about participation.

Once you've enrolled in a trial, our research teams are here with you and your family throughout the process. We're always here to answer any questions about the trial and help with coordinating appointments.

View all clinical trials.

Contact Info
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Mother Infant Research Institute 
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Tufts Medical Center
800 Washington, Box 394
Boston, MA 02111

Contact information

Mailing address

Tufts Medical Center 
Mother Infant Research Institute
800 Washington St. 
Box 394 
Boston, MA 02111 
Tel: 617.636.1468

Office Location

The Mother Infant Research Institute is located in the Tupper Research building, 9th floor, 15 Kneeland St., Boston, MA. The building is locked and accessible from the street only with a Tufts Medical Center identification badge.

For visitors with scheduled appointments, please call 617.636.1468 prior to arriving and a member of our staff will meet you at the entrance.

Investigator contact information

Perrie O’Tierney-Ginn, PhD 
Executive Director, Mother Infant Research Institute
Research Associate Professor of Obstetrics & Gynecology, Tufts University School of Medicine
Friedman School of Nutrition Science and Policy
email: Perrie.F.OTierney-Ginn@tuftsmedicine.org


Patrick M. Catalano, MD 
Vice Chair of Obstetrics & Gynecology Research 
Professor of Obstetrics & Gynecology, Tufts University School of Medicine 
Friedman School of Nutrition Science and Policy 
email: Patrick.Catalano@tuftsmedicine.org


Michael House, MD 
Associate Professor of Obstetrics and Gynecology, Tufts University School of Medicine 
Maternal-Fetal Medicine Specialist, Tufts Medical Center 
email: Michael.House@tuftsmedicine.org


Sebastian Ramos, MD
Assistant Professor of Obstetrics and Gynecology, Tufts University School of Medicine
Maternal-Fetal Medicine Specialist, Tufts Medical Center
email: Sebastian.Ramos@tuftsmedicine.org


Elizabeth Yen, MD 
Assistant Professor of Pediatrics, Tufts University School of Medicine 
Neonatologist, Tufts Medical Center 
email: Elizabeth.Yen2@tuftsmedicine.org

Pregnant woman with fruits and vegetables

Recruiting study participants now

Produce prescriptions on maternal and birth outcomes: A food is medicine intervention among pregnant women, aims to evaluate the feasibility of implementing produce prescriptions in our prenatal care clinics at Tufts Medical Center

Articles
Produce Rx Sows the Seeds of Nutritional Health for Generations
April 15, 2024
Poor nutrition is devastating the health of American families. A prescription produce program, from Tufts Medicine’s Mother Infant Research Institute and the Friedman School of Nutrition Science and Policy at Tufts University, is delivering nutritious foods and a healthy start to Massachusetts families.
Announcements
Dr. Sebastian Ramos Promoted to MIRI PI
April 2, 2024
Dr. Sebastian Ramos of Obstetrics and Gynecology has been promoted to Principal Investigator at MIRI.
Articles
MIRI Will Collaborate on Tufts Springboard Grant
April 1, 2024
Study Examines the paternal role in intergenerational impacts of stress.
Infant Vision Health and Prenatal Drug Exposure
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Vision health
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All genders
person-wave 0-5
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Recruiting now
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SPITSS
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Sepsis
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All genders
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No minimum age

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Placental function in early pregnancy
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Pregnancy
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Female
person-wave 18-45
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Recruiting now
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