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department
We are compassionate caregivers of patients living with serious illnesses, helping them manage their symptoms, navigate complex care systems and live a good life as long as possible.
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This is a 10-year, longitudinal, observational study of patients with PSC to address knowledge gaps in the clinical presentation, natural history, epidemiology, progression, and outcomes of PSC. In addition, the study will address prognostic models and biomarker development. There will be an option to participate in specimen repository at each site for translational studies of genomics and novel biomarkers discovery.
department
The Division of General Internal Medicine is here to provide comprehensive healthcare services in the communities where our patients live and work. Our teams of primary and specialty care physicians, nurses and administrative staff have one priority: to keep you as healthy as possible.
department
Our team of specialized physicians are experts in the diagnosis and treatment of gastrointestinal diseases. You can trust us to provide the highest quality of care with our expertise and dedication.
department
We understand that one approach to cancer care does not fit every patient. That’s why our team of specialists works closely with you, the referring physician, to create a treatment plan that considers your patient's needs and encompasses our wide range of state-of-the-art cancer treatment options.
department
The Division of Geographic Medicine + Infectious Diseases is an international center of excellence in infectious disease, inpatient and outpatient treatment, research, and infectious disease fellowship training.
clinical trial
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The purpose of this study is to establish a large, international, web based registry, using the Surgical Outcomes System (SOS), to collect baseline characteristics of patients undergoing orthopaedic and sports medicine, arthroscopy, and related surgery, and the subsequent outcomes and costs-effectiveness associated with the surgical procedures. Additionally, baseline and outcome data for non-operative treatment procedures will b collected using the same measures in order to compare to surgical outcomes.
department
Since the late 19th century, the Department of Pediatrics has been improving and redefining pediatric care, research and training.
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ARCADIA is a multicenter, biomarker-driven, randomized, double-blind, active-control, phase 3 clinical trial of apixaban versus aspirin in patients who have evidence of atrial cardiopathy and a recent stroke of unknown cause. Eleven hundred subjects will be recruited over 2.5 years at 120 sites in the NIH StrokeNet consortium. Subjects will be followed for a minimum of 1.5 years and a maximum of 4 years for the primary efficacy outcome of recurrent stroke and the primary safety outcomes of symptomatic intracranial hemorrhage and major hemorrhage other than intracranial hemorrhage.
clinical trial
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This is a Prospective, multicenter, randomized, parallel-controlled, open-label two arm trial with an adaptive design. Eligible subjects will be randomized in a 1:1 ratio to PCI with Impella CP® (Intervention Group) versus standard of care PCI with or without IABP (Control Group). Approximately 1252 subjects will be randomized in a 1:1 ratio to PCI + Impella vs. PCI ± IABP.
department
Providing cutting-edge care for even the most complex diseases through every step of treatment and recovery.
department
The Department of Medicine helps us stand tall as one of the country’s leading health systems. While we take great pride in celebrating our department’s accomplishments, it’s our commitment to training tomorrow's primary care doctors, hospitalists and subspecialists that moves the needle of clinical care forward.
clinical trial
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This is a prospective, multi-center clinical study to validate the effectiveness of the Boppli Blood Pressure Monitor as compared to an invasive arterial reference. This study will evaluate the accuracy and precision of the Boppli system for continuous blood pressure monitoring by comparing SBP, DBP, and MAP against the reference methodology in pediatric and neonatal populations.
clinical trial
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Gore has developed and manufactures the GORE® SYNECOR Intraperitoneal Biomaterial device (GORE® SYNECOR IP Device) to offer clinicians a mesh material intended for the repair of ventral/incisional hernias that may require the addition of a nonabsorbable reinforcing or bridging material. The primary study objective is to assess SYNECOR Biomaterial performance on incisional hernia patients over an extended amount of time through multiple methods. The secondary study objective is to conduct configuration-specific assessments to address areas of medical interest.
clinical trial
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This phase II trial tests how well an imaging procedure called fludeoxyglucose F-18 (FDG) positron emission tomography/computed tomography (PET/CT) works in predicting response to standard of care chemotherapy prior to surgery in patients with HER2-positive stage IIa-IIIc breast cancer. FDG is a radioactive tracer that is given in a vein before PET/CT imaging and helps to identify areas of active cancer. PET and CT are imaging techniques that make detailed, computerized pictures of areas inside the body.
department
The understanding of cancer is growing every day and our clinicians are making a significant impact on how the world researches, teaches and delivers care to improve quality and quantity of life.
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This study aims to learn more about the investigational drug, ASTX727, and another drug, venetoclax, when given in combination. It also aims to evaluate potential pharmocokinetics (PK) interactions for the treatment of newly diagnosed acute myeloid leukemia (AML) in adults who are age 75 years or older, or who have comorbidities that preclude use of intensive induction chemotherapy.

The primary purpose of the study is to rule out drug-drug interactions between ASTX727 and venetoclax combination therapy.
clinical trial
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This is a single center prospective cohort study. The cohort (interventional) patients will receive the study intervention (ABCLO). The control group retrospective patients that were previously managed at the same center, regardless of the technique or the device used to close the OA.
department
The Department of Ophthalmology and New England Eye Center makes healthier possible with expert diagnosis and treatment of eye diseases and visual problems. Beyond our clinical care, we’re leading the way to the future of ophthalmic care through training and education programs, eye research and ophthalmic technology development.